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"There is concern about hepatitis C and HIV the risk of transmission from sexual contact. So, there is a need for this kind of drug," said James O. Miller, M.D., assistant professor in the Department of Medicine and director the Division of Infectious Diseases at UConn Health. "But there is a great deal of uncertainty about whether it is safe, effective and cost for this population."
According to the U.S. Centers for Disease Control, the top five causes of death in the United States are AIDS, cancer of the liver (including cancer), chronic lower respiratory disease, firearm-related injuries and AIDS/HIV.
Miller said the new study included data on more than 900 people with hepatitis C over a four-year period (2005 to 2009) and examined how long it took for people with hepatitis C to receive the first prescription of combination drug, and what the cost would be.
The study found no significant differences in the risk of hepatitis C infection, HIV transmission or mortality associated with taking the drugs, according to Journal of Infection Control.
In addition, there was no difference in the frequency with which people took these drugs, either single-drug or combination, according to the report.
"The bottom line is that this a very safe and effective therapy" to prevent infection or spread of HIV, said Jennifer R. Oster, Ph.D., assistant professor in the Department of Medicine, who led the study with Miller. "If it didn't work, there would be another very expensive medicine to treat these infections."
One other note about the report: analysis included people of all ages who had been treated at Connecticut's University Hospital — including many who had been treated for liver problems years before. Thus, the results could not be generalized to other medical centers or the general population, which would have affected the overall findings.
Miller said the findings were important because they may provide information about the effectiveness of drugs to prevent transmission certain types of hepatitis that need to be studied in the future.
The prescription medications he and his colleagues administered included four different drugs and were designed to control hepatitis C for six months to one year. For example, Zovirax
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The research also included use of several other medications to treat conditions related the virus that cause hepatitis C, including Sovaldi ($84,500 a-year), Keytruda ($31,000 and Tivicay ($34,800 a-year). As a small team we're constantly striving towards the ultimate goal of making best video game experience possible and for a long time now we've been putting our head down working on the next generation of our favorite adventure games. It hasn't always been easy, but we've finally managed to bring us the next generation of Tomb Raider, and the team's enthusiasm is at an all-time high.
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However, it's also clear to us that we've achieved an incredibly high standard of quality with Tomb Raider that our team simply can not match. This is something we'd have considered, and would never if you asked us just 18 months ago. It's difficult to imagine a single person working their way up to managing a team of more than 60 full-time Zovirax 60 Pills 200mg $159 - $2.65 Per pill developers for three or four years. Our hope at this juncture is that by launching the game for pre-purchase on PC gamers and early owners on Xbox One will be able to have a great experience.
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The manufacturer does not provide information about how many people have been prescribed the drug since its launch.
The company has been contacted for this story but said it had no information to share at the moment.
A spokesperson for the Medicines and Healthcare products Regulatory Agency (MHRA) told Newsweek the drug was licensed in 2008 but not yet available.
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Methotrexate affects a person's metabolism and should not be used in those who are elderly, already have kidney or liver problems which could damage the liver and kidneys, or to prevent the body using its natural detoxification mechanisms.
Methotrexate has been around for more than five decades and is in a class of medicines called statins. It is only taken orally and the dosage of drug prescribed is around five milligrams.
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